Prototype Open Knowledge Network (Proto-OKN)

Connecting Biomedical Information on Earth and in Space Via the SPOKE
Knowledge Graph

PROJECT OVERVIEW
Through this project, development of SPOKE is directed towards space biology and medicine to facilitate bi-directional translation of knowledge and identification of meaningful analogues to maximize ongoing efforts to make humans a multi-planetary species. 
 

information integrations from SPACE
Proposed information integration from Space and Earth sources to build realistic analogues that can improve experience and mitigate risks of spaceflight.

The first aim is to integrate SPOKE with primary data from NASA’s Open Data Science Repository (OSDR), starting with the GeneLab platform - a massive repository of
more than 100,000 experiments of relevance to space flight.

The second aim is integration of social determinants of health (SDOH) into SPOKE. Studying SDOH on Earth can provide valuable insights and analogues for understanding and addressing health issues during spaceflight. This aim will involve use of de-identified electronic health records and integration of data from multiple population-based databases from the Centers for Disease Control and prevention, Environmental
Protection Agency, and the World Health Organization.

 

OSDR-SPOKE Data Fabric

The SPOKE integration with a select number of OSDR studies is now available!

You may access the OSDR-SPOKE Data Fabric via graphical user interface available at NASA GeneLab visualization portal.

OSDR-SPOKE Data Fabric Visualization Example Video

 

 

OSDR-SPOKE Data Fabric Integration Schema

NASA Genelab study schema

 

 

GeneLab Study Statistics

study

GeneLab Visualization

 

SOCIAL DETERMINANTS OF HEALTH

 

 

INFORMATIONAL LINKS
 

GeneLab-SPOKE Demo

UC Space Health
NASA Open Science Data Repository (OSDR)

 

NASA AWG Info

NASA AWG Forum



FUNDING

NSF Proto-OKN Program

 

NEWS & EVENTS
 

UCSF Innovation Showcase at JPM25
MATE bioservices selected to be in the “HIGHLIGHT” Showcase which is comprised of tabletop exhibits in the main reception.

NASA Human Research Program Investigators’ Workshop Poster 

UCSF Research AI Day Poster Presentation