Connecting Biomedical Information on Earth and in Space Via the SPOKE
Knowledge Graph
PROJECT OVERVIEW
Through this project, development of SPOKE is directed towards space biology and medicine to facilitate bi-directional translation of knowledge and identification of meaningful analogues to maximize ongoing efforts to make humans a multi-planetary species.
The first aim is to integrate SPOKE with primary data from NASA’s Open Data Science Repository (OSDR), starting with the GeneLab platform - a massive repository of
more than 100,000 experiments of relevance to space flight.
The second aim is integration of social determinants of health (SDOH) into SPOKE. Studying SDOH on Earth can provide valuable insights and analogues for understanding and addressing health issues during spaceflight. This aim will involve use of de-identified electronic health records and integration of data from multiple population-based databases from the Centers for Disease Control and prevention, Environmental
Protection Agency, and the World Health Organization.
GENELAB – SPOKE INTEGRATION
The SPOKE graphical user interface is available at NASA GeneLab here: https://visualization.genelab.nasa.gov/data/
SOCIAL DETERMINANTS OF HEALTH
INFORMATIONAL LINKS
UC Space Health
NASA Open Science Data Repository (OSDR)
FUNDING
NEWS & EVENTS
UCSF Innovation Showcase at JPM25
MATE bioservices selected to be in the “HIGHLIGHT” Showcase which is comprised of tabletop exhibits in the main reception.